Endocrine Abstracts

Introduction: Resistance to thyroid hormone (TH) can be caused by a failure of TH to enter the cell, or by a lack of action of intracellular TH.Cases: Patient A, a 60-year-old man, presented with an elevated TSH (15.8 mU/l (reference range: 0.4–4.3 mU/l)), an elevated FT4 (29.5 pmol/l (11–25 pmol/l)), and a normal T3. Reverse T3 (rT3), the inactive metabolite of T4, was clearly elevated (0.82 nmol/l (0.14–0.34 nmol/l)). His medical history...